Abstract Search

ea0032p594 | Female reproduction | ECE2013

PCOS subphenotypes stratification reveals an apparent increase of metabolic syndrome frequency in patients with concomitant hyperandrogenism and menstrual irregularities

Baculescu Nicoleta , Radian Serban , Gussi Ilinca , Gheorghiu Monica , Poiana Catalina , Grigorescu Florin , Coculescu Mihail

Background: PCOS-associated increased metabolic risk may be selective, owing to its heterogeneous nature. Identification of high-risk individuals could enable better studies and prevention of complications.Aim: To characterize the metabolic risk, as metabolic syndrome (MetS), of specific PCOS subphenotypes.Subjects and methods: Romanian PCOS (Rotterdam criteria) and 64 controls, 1835 years. PCOS subphenotypes were defined: i)...

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ea0022p498 | Female reproduction | ECE2010

CAG repeat alleles of the androgen receptor are associated with polycystic ovary syndrome (PCOS) in the Romanian population

Radian Serban , Baculescu Nicoleta , Aflorei Daniela , Gussi Ilinca , Vladoiu Suzana , Ianas Olga , Grigorescu Florin , Coculescu Mihai

Background: Androgen receptor (AR) activity is modulated by the length of CAG-repeat polymorphism in exon 1. Published data suggest association between CAG-repeat alleles and PCOS, but not all studies confirmed this finding.Aim: To test association of AR alleles with PCOS and clinical and biochemical signs of hyperandrogenism.Study design: Casecontrol association study, approved by the institutional ethical committee, of 137 ...

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Endocrine Abstracts

PCOS subphenotypes stratification reveals an apparent increase of metabolic syndrome frequency in patients with concomitant hyperandrogenism and menstrual irregularities

CAG repeat alleles of the androgen receptor are associated with polycystic ovary syndrome (PCOS) in the Romanian population

BiosciAbstracts